Report a Disease

Diseases of major public health concern because of severity or potential for epidemic spread, report immediately by telephone upon recognition of a case, suspected case, or positive laboratory result.

• Anthrax
• Botulism
• Diphtheria
• Free-living amoeba infection
• Influenza A, novel virus infection
• Measles
• Meningococcal disease
• Middle East Respiratory Syndrome (MERS)
• Plague
• Rabies, human
• Rubella (not congenital)
• Severe acute respiratory syndrome (SARS)
• Smallpox
• Tularemia, inhalation
• Viral hemorrhagic fever (Ebola, Lassa, Marburg, Crimean-Congo)

Also report any unexpected pattern of cases, deaths, or increased incidence of any disease of major public health concern that may indicate a newly recognized agent, outbreak, epidemic, public health hazard, or act of bioterrorism.

Diseases of public health concern needing timely response, report by the end of the next business day after a case, suspected case, or positive laboratory result is known.

• Acute flaccid myelitis (AFM)
• Anaplasmosis
• Arboviral disease (Chikungunya, EEE, La Crosse, Powassan, St. Louis encephalitis, West Nile, Western equine encephalitis, Yellow fever, Zika, other)
• Babesiosis
• Brucellosis
• Campylobacteriosis
• Candida auris
• Carbapenemase-producing organisms (CPO)
• Chancroid
• Chlamydia trachomatis infections
• Cholera
• Coccidioidomycosis
• COVID-19-associated hospitalization
• Creutzfeldt-Jakob disease (CJD)
• Cronobacter (invasive, infants under 12 months)
• Cryptosporidiosis
• Cyclosporiasis
• Dengue
• E. coli O157:H7 and Shiga toxin-producing E. coli (STEC)
• Ehrlichiosis
• Giardiasis
• Gonorrhea (Neisseria gonorrhoeae)
• Haemophilus influenzae (invasive disease)
• Hantavirus
• Hemolytic uremic syndrome (HUS)
• Hepatitis A
• Hepatitis B (non-perinatal)
• Hepatitis B (perinatal)
• Hepatitis C (non-perinatal)
• Hepatitis C (perinatal)
• Hepatitis D (delta hepatitis)
• Hepatitis E
• Influenza-associated hospitalization
• Influenza-associated pediatric mortality
• Legionnaires' disease
• Leprosy (Hansen disease)
• Leptospirosis
• Listeriosis
• Lyme disease
• Malaria
• Melioidosis
• Meningitis, bacterial
• Mpox
• Mumps
• Pertussis
• Poliomyelitis (including vaccine-associated cases)
• Psittacosis
• Q fever
• Respiratory syncytial virus (RSV)-associated hospitalization
• Rubella (congenital)
• Salmonella Paratyphi infection
• Salmonella Typhi infection (typhoid fever)
• Salmonellosis
• Shigellosis
• Spotted fever rickettsiosis, including RMSF
• Staphylococcus aureus (VRSA / VISA)
• Streptococcal disease, group A, invasive (IGAS)
• Streptococcal disease, group B, in newborn
• Streptococcal toxic shock syndrome (STSS)
• Streptococcus pneumoniae, invasive disease (ISP)
• Syphilis
• Tetanus
• Toxic shock syndrome (TSS)
• Trichinellosis
• Tuberculosis (active disease; latent infection in a child 2 or younger)
• Tularemia, non-inhalation
• Varicella
• Vibriosis
• Yersiniosis

Report an outbreak, unusual incident, or epidemic of other diseases (e.g., histoplasmosis, pediculosis, scabies, staphylococcal infections) by the end of the next business day. Outbreak types include:

• Community
• Foodborne
• Healthcare-associated
• Institutional
• Waterborne
• Zoonotic